Physiological Control Systems

EE046331

Spring 2003

[Announcements]    [Staff]    [Course description]   [Grades]    [Exercises]    [Recommended reading]

Announcements

• Updated 14th July 2003:
   
  All your homework exercises have been checked and will be returned today.
  Official solutions can be found on the net or outside my office.
   
  The final homework grades can also be found on the net. As mentioned before the grade is the average of the best 5 homework exercises.
   
  Appeals for the homework grade can be done NO LATER than this coming Thursday 17th July 2003.
  
   
• updated 15th May 2003:
  The midterm exam grades have been updated  on the site.

• updated 21st March 2003:
  The mailing list server has come back to life.
  To join the list

• updated 19th March 2003:
  The makeup tutorial will be held on Wednesday 02nd April 2003 at 12:30 in Meyer 353.

Note: there would be no tutorial in the first week

First lecture: Wednesday March 5, 10:30am, Electrical Engineering building room 353
First tutorial: Wednesday March 12, 8:30am, Electrical Engineering building room 353

Staff

Lecturer:  Dr. Amir Karniel                                    email: karniel@ee.technion.ac.il

Teaching Assistant:  Hayley Binia Wolman              email: hayleybw@tx.technion.ac.il

Course description

Artificial organs and neural prosthesis are the state of the art in biomedical engineering research.  These systems should work harmonically with the biological system.  Therefore an important aspect in the design of such artificial systems is a proper model for the biological system that can be used to analyze the combined biological artificial behavior.

This course introduces basic tools for physiological system analysis.  

Most of the course is devoted to computational motor control, which is the study of the biological motor control system using quantitative models.  At the last lectures the cardiovascular and temperature regulation systems are described.

Main topics:

• Biological motor control  
• Feedback and Feedforward, Linear and nonlinear control
• Adaptive control and parameter estimation
• Neural networks for control
• The cardiovascular system and control of cardiac pacemakers
• Temperature regulation

 Prerequisite INT.TO BIOLOGICAL SIGNALS & SYSTEMS 046326. 

Information for students [pdf]

Introductory lecture slides [pdf]

Grades

Midterm Exam:

Exam Paper

Exam Grades

Homework Exercises:

Homework Grades

Exercises

Tutorials

Homework Exercises

Recommended reading

Books

Kandel ER, Schwartz JH, Jessell TM, Principles of neural science (4th Ed.), McGraw-Hill, 2000

McMahon TA, Muscles, Reflexes and Locomotion, Princton Univ. Press 1988

Arbib MA, The handbook of brain theory and neural networks,  MIT press 1995, 2nd ed, 2003

Craig JJ,  “Introduction to robotics” 2nd Edition  1989

Papers

D. T. McRuer, R. E. Magdaleno, and G. P. Moore, "A neuromuscular actuation system model," IEEE Transactions on Man-Machine Systems, vol. MMS-9, pp. 61-71, 1968.  [pdf zipped]

G. F. Inbar and A. Yafe, "Parameter and Signal Adaptation in the Stretch Reflex Loop," in Prog Brain Res, vol. 44, S. Homma, Ed. Amsterdam: Elsevier, 1976, pp. 317-337. [pdf zipped]

A. Karniel and G. F. Inbar, "Human motor control: Learning to control a time-varying, nonlinear, many-to-one system," IEEE Transactions on Systems Man and Cybernetics Part C-Applications and Reviews, vol. 30, pp. 1-11, 2000. [pdf]

T. Flash and N. Hogan, "The coordination of arm movements: An experimentally confirmed mathematical model.," Journal of Neuroscience, vol. 5, pp. 1688-1703, 1985. [pdf]

R. Shadmehr and F. A. Mussa-Ivaldi, "Adaptive representation of dynamics during learning of a motor task," Journal of Neuroscience, vol. 14, pp. 3208-3224, 1994. [pdf]

M. I. Jordan, "Computational aspects of motor control and motor learning," in Handbook of Perception and Action: Motor Skills, H. Heuer and S. Keele, Eds. New York: Academic Press, 1996.  [ms, pdf]

G. F. Inbar, R. Heinze, K. N. Hoekstein, H.-D. Liess, K. Stangl, and A. Wirtzfeld, "Development of a closed-loop pacemaker controller regulating mixed venous oxygen saturation level," IEEE Transactions on Biomedical Engineering, vol. 35, pp. 679-690, 1988. [pdf]

A. C. Brown and G. L. Brengelmann, "The interaction of peripheral and central inputs in the temperature regulation system," in Physiological and Behavioral Temperature Regulation, J. D. Hardy, A. P. Gagge, and J. A. J. Stolwijk, Eds., 1970, pp. 684-702. [pdf zipped]